BDBM145591 US8952169, 389
SMILES CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)C2CC2)CCC2(CC2)CC1
InChI Key InChIKey=GFDXIUXAFNREKM-UHFFFAOYSA-N
Data 23 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 145591
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human Nav1.6 alpha subunit expressed in HEK293 cells co-expressing beta1 subunit at -35 mV holding potential by PatchXpress automated v...More data for this Ligand-Target Pair